Age and obesity-driven changes in the extracellular matrix of the primary tumor and metastatic site influence tumor invasion and metastatic outgrowth
S. J. Conner, J. R. Guarin, H. Borges, K. J. Salhany, D. N. Mensah, G. A. Hamilton, G. H. Le, M. J. Oudin
This study shows that age and obesity alter the extracellular matrix (ECM) in primary tumors and metastatic sites, promoting tumor invasion and metastasis in triple-negative breast cancer.
bioRxiv · Aug 24, 2023 · PreprintCancer Biology