Pre-existing heterogeneity facilitates development of heteroresistance upon gene acquisition
S. Jaggavarapu, D. A. Hufnagel, D. S. Weiss
The paper shows that pre-existing phenotypic heterogeneity can lead to heteroresistance upon gene acquisition, highlighting a mechanism for antibiotic resistance evolution.
bioRxiv · Jul 24, 2023 · PreprintMicrobiology