Evolutionary states and trajectories characterized by distinct pathways stratify ovarian high-grade serous carcinoma patients
A. Lahtinen, K. Lavikka, Y. Li, A. Virtanen, S. Jamalzadeh, K. Huhtinen, O. Carpen, S. Hietanen, A. Häkkinen, J. Hynninen, J. Oikkonen, S. Hautaniemi
This study identifies three evolutionary states of ovarian high-grade serous carcinoma using whole-genome sequencing and links them to distinct therapeutic targets.
bioRxiv · Aug 30, 2022Cancer Biology