Dissecting the roles of Haspin and VRK1 in Histone H3 threonine-3 phosphorylation during mitosis
T. N. Cartwright, R. J. Harris, S. K. Meyer, N. A. Watson, C. Tan, F. Wang, J. M. G. Higgins
This study investigates the roles of Haspin and VRK1 in phosphorylating histone H3 during mitosis, finding that VRK1 does not directly phosphorylate H3T3 or H3S10, while Haspin is essential for H3T3ph.
bioRxiv · Sep 7, 2021Cell Biology