In-depth characterization of the serum antibody epitope repertoire in inflammatory bowel disease using phage-displayed immunoprecipitation sequencing
A. R. Bourgonje, S. Andreu-Sanchez, T. Vogl, S. Hu, A. V. Vila, R. Gacesa, S. Leviatan, A. Kurilshikov, S. Klompus, I. N. Kalka, H. M. van Dullemen, A. Weinberger, M. C. Visschedijk, E. A. M. Festen, K. N. Faber, , R. K. Weersma
This study identifies distinct antibody epitope repertoires in IBD patients using PhIP-seq, revealing differentially abundant antibodies associated with disease subtypes and features.
bioRxiv · Dec 7, 2021Immunology