Author

C. Wijmenga

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Cell Biology· 2 Immunology· 2

Signature Assays, Organisms & Methods

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Organism:human· 8 Research Focus:cell type annotation· 6 Research Focus:differential expression· 4 Approach:experimental assay· 4 Assay:metagenomics· 4 Approach:statistical model· 4 Research Focus:clustering· 3 Assay:bulk RNA-seq· 2

Frequent Co-Authors

A. Zhernakova· 7 shared J. Fu· 7 shared A. Kurilshikov· 6 shared R. K. Weersma· 5 shared S. Andreu-Sanchez· 5 shared A. Vich Vila· 4 shared R. Gacesa· 4 shared T. Sinha· 4 shared

Activity by Year

2020-2024 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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Curved chords = mutual co-authorship

7 shared papersMicrobiology

A. Zhernakova

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

High-resolution analysis of the treated coeliac disease microbiome reveals strain-level variation

J. Slager, H. L. Simpson, R. Gacesa, L. Chen, I. L. Tan, J. Gelderloos, A. Maatman, C. Wijmenga, A. Zhernakova, J. Fu, R. K. Weersma, G. Gonera, I. H. Jonkers, S. Withoff

This study analyzes the gut microbiome of treated coeliac disease patients at strain level, revealing increased interindividual variation and specific microbial associations.

bioRxiv · Mar 8, 2024Microbiology

An iPSC-derived small intestine-on-chip with self-organizing epithelial, mesenchymal and neural cells

R. Moerkens, J. Mooiweer, A. D. Ramirez-Sanchez, R. Oelen, L. Franke, C. Wijmenga, R. J. Barrett, I. H. Jonkers, S. Withoff

This paper develops a hiPSC-derived intestine-on-chip system that mimics the human small intestine's epithelial, mesenchymal, and neural composition and function.

bioRxiv · Jan 4, 2024Cell Biology

Mother-Infant Gut Viruses and their Bacterial Hosts: Transmission Patterns and Dynamics during Pregnancy and Early Life

S. Garmaeva, T. Sinha, A. Gulyaeva, N. Kuzub, J. E. Spreckels, S. Andreu-Sanchez, R. Gacesa, A. Vich Vila, S. Brushett, M. Kruk, J. Dekens, J. Sikkema, F. Kuipers, A. Shkoporov, C. Hill, , A. Zhernakova

bioRxiv · Aug 21, 2023Microbiology

Genetic, parental and lifestyle factors influence telomere length

S. Andreu-Sanchez, G. Aubert, A. Ripoll-Cladellas, S. Henkelman, D. V. Zhernakova, T. Sinha, A. Kurilshikov, M. C. Cenit, M. J. Bonder, Lifelines cohort study, L. Franke, C. Wijmenga, J. Fu, M. G. P. van der Wijst, M. Mele, , A. Zhernakova

This study identifies factors influencing telomere length across blood cell types, showing genetic, parental, and lifestyle effects, with maternal age's impact mediated by epigenetics.

bioRxiv · Dec 14, 2021Cell Biology

In-depth characterization of the serum antibody epitope repertoire in inflammatory bowel disease using phage-displayed immunoprecipitation sequencing

A. R. Bourgonje, S. Andreu-Sanchez, T. Vogl, S. Hu, A. V. Vila, R. Gacesa, S. Leviatan, A. Kurilshikov, S. Klompus, I. N. Kalka, H. M. van Dullemen, A. Weinberger, M. C. Visschedijk, E. A. M. Festen, K. N. Faber, , R. K. Weersma

This study identifies distinct antibody epitope repertoires in IBD patients using PhIP-seq, revealing differentially abundant antibodies associated with disease subtypes and features.

bioRxiv · Dec 7, 2021Immunology

Genetic, environmental and intrinsic determinants of the human antibody epitope repertoire

S. Andreu-Sanchez, A. R. Bourgonje, T. Vogl, A. Kurilshikov, S. Leviatan, A. J. Ruiz Moreno, S. Hu, T. Sinha, A. Vich Vila, S. Klompus, I. Kalka, K. de Leeuw, S. Arends, I. H. Jonkers, S. Withoff, , A. Zhernakova

This study uses PhIP-Seq to analyze antibody repertoires in 1,443 individuals, showing genetic and environmental factors influence antibody diversity and phenotype associations.

bioRxiv · Dec 7, 2021Immunology

Discovery, diversity and functional associations of crAss-like phages in human gut metagenomes from four Dutch cohorts

A. Gulyaeva, S. Garmaeva, R. A. A. A. Ruigrok, D. Wang, N. P. Riksen, M. G. Netea, C. Wijmenga, R. K. Weersma, J. Fu, A. Vich Vila, A. Kurilshikov, A. Zhernakova

The paper discovers new crAss-like phage species and explores their diversity, genomic features, host associations, and links to human health phenotypes in Dutch gut metagenomes.

bioRxiv · Jun 1, 2021Microbiology

The Dutch Microbiome Project defines factors that shape the healthy gut microbiome

R. Gacesa, A. Kurilshikov, A. Vich Vila, T. Sinha, M. A. Y. Klaassen, L. A. Bolte, S. Andreu-Sanchez, L. Chen, V. Collij, S. Hu, J. A. M. Dekens, V. C. Lenters, J. R. Bjork, J. C. Swarte, M. A. Swertz, , R. K. Weersma

This study identifies environmental and lifestyle factors shaping the gut microbiome in a large Dutch cohort, finding that most microbiome variation is due to environment rather than genetics.

bioRxiv · Nov 27, 2020 · PreprintMicrobiology