A novel family of sugar-specific phosphodiesterases that remove zwitterionic modifications of N-acetylglucosamine
S. L. Fossa, B. P. Anton, D. W. Kneller, L. M. C. Petralia, M. L. Boisvert, S. Vainauskas, C. H. Hokke, J. M. Foster, C. H. Taron
This study identifies and characterizes a novel phosphodiesterase, GlcNAc-PDase, that specifically removes zwitterionic modifications from GlcNAc-6-PC and GlcNAc-6-PE in parasitic nematodes.
bioRxiv · Jun 1, 2023Biochemistry