When is a slender not a slender? The cell-cycle arrest and scarcity of slender parasites challenges the role of bloodstream trypanosomes in infection maintenance
S. Larcombe, E. M. Briggs, N. Savill, B. Szoor, K. Matthews
This study shows that Trypanosoma brucei cell-cycle arrest is irreversible and that proliferating parasites are rare in established infections, suggesting bloodstream forms are adapted for transmission rather than infection maintenance.
bioRxiv · Apr 6, 2023 · PreprintMicrobiology