S. Lion

Double Trouble: Multiple infections and the coevolution of virulence and resistance in nested host-parasite populations

The paper analyzes the coevolution of parasite virulence and host resistance under different infection regimes using a nested co-evolutionary model.

Effect of unequal vaccination coverage and migration on long-term pathogen evolution in a metapopulation

The paper analyzes how spatial vaccination coverage and migration affect pathogen evolution in a metapopulation, showing that vaccines reducing virulence can lead to more virulent pathogens and strain coexistence.

Extending eco-evolutionary theory with oligomorphic dynamics

This paper introduces a new theoretical framework called oligomorphic dynamics to integrate quantitative genetics and adaptive dynamics, addressing limitations in modeling eco-evolutionary processes with multimodal trait distributions and environmental feedback.

An epi-evolutionary model for predicting the adaptation of spore-producing pathogens to quantitative resistance in heterogeneous environments

This paper develops an epi-evolutionary model to predict how spore-producing pathogens adapt to quantitative resistance in heterogeneous environments, showing that resistance targeting infection efficiency drives pathogen diversification and affects epidemiological control.

Multi-morph eco-evolutionary dynamics in structured populations

The paper develops a theoretical framework to model eco-evolutionary dynamics in structured populations with multimodal trait distributions, demonstrating its application to migration-selection models.

Evolution of class-structured populations in fluctuating environments

The paper develops a theoretical framework to analyze how periodic environmental fluctuations influence life-history trait evolution in structured populations, with applications to pathogen dynamics.

The impact of antigenic escape on the evolution of virulence

This paper models how antigenic drift and escape influence the evolution of virulence, showing that non-equilibrium dynamics select for more virulent pathogens than classical R0 maximization.

Evolutionary emergence of infectious diseases in heterogeneous host populations

This paper develops a theoretical model to predict pathogen emergence based on host population heterogeneity and validates it with experiments using bacteriophages and CRISPR-resistant bacteria.

On the dynamics of reproductive values and phenotypic traits in class-structured populations

The paper develops a dynamic framework for reproductive values in class-structured populations, showing how time-dependent weights can remove non-selective effects from trait dynamics.