Author

S. Melhem

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:comparative / phylogenetic analysis· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Wosztyl· 1 shared D. Chen· 1 shared H. Seelaar· 1 shared J. Vacquer-Alicea· 1 shared J. Van Swieten· 1 shared L. A. Joachimiak· 1 shared M. I. Diamond· 1 shared S. Bali· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperBiophysics

A. Wosztyl

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1 paper

Recent·Most cited

FTD-tau S320F mutation stabilizes local structure and allosterically promotes amyloid motif-dependent aggregation

D. Chen, A. Wosztyl, V. Mullapudi, S. Bali, J. Vacquer-Alicea, S. Melhem, H. Seelaar, J. Van Swieten, M. I. Diamond, L. A. Joachimiak

This study investigates how the FTD-tau S320F mutation stabilizes local structure and promotes amyloid motif-dependent aggregation through allosteric effects.

bioRxiv · Aug 11, 2022 · PreprintBiophysics