The P5-ATPase ATP13A1 modulates MR1-mediated antigen presentation
C. A. Kulicke, E. De Zan, Z. Hein, C. Gonzalez-Lopez, S. Ghanwat, N. Veerapen, G. Besra, P. Klenerman, J. C. Christianson, S. Springer, S. Nijman, V. Cerundolo, M. Salio
This study identifies ATP13A1 as a key regulator of MR1 surface expression through CRISPR/Cas9 knockout experiments in human cell lines.
bioRxiv · May 26, 2021 · PreprintImmunology