CIGB-300 peptide targets the CK2 phospho-acceptor domain on Human Papillomavirus E7 and disrupts the Retinoblastoma (RB) complex in cervical cancer cells
A. d. l. C. Ramon, O. Basukala, P. Massimi, M. Thomas, Y. Perera, L. Banks, S. Perea
This study investigates how CIGB-300 peptide targets HPV-16 E7, disrupts CK2-mediated phosphorylation, and affects the E7-pRB interaction in cervical cancer cells.
bioRxiv · Jun 23, 2022Cancer Biology