Recurrent loss of an immunity gene that protects Drosophila against a major natural parasite
R. Arunkumar, S. O. Zhou, J. P. Day, S. Bakare, S. Pitton, C.-Y. Hsing, S. O Boyle, J. Pascual-Gil, B. Clark, R. J. Chandler, A. B. Leitao, F. M. Jiggins
The paper identifies recurrent loss-of-function mutations in the Drosophila immunity gene Lectin-24A, showing natural selection favors these mutations in some populations due to a pleiotropic cost of expression.
bioRxiv · May 27, 2022 · PreprintEvolutionary Biology