Mitophagy contributes to alpha-tocopheryl succinate toxicity in GSNOR-deficient hepatocellular carcinoma.
S. Rizza, L. Di Leo, S. Mandatori, D. De Zio, G. Filomeni
This study shows that GSNOR-deficient hepatocellular carcinoma cells have defective mitophagy, which contributes to their sensitivity to alpha-tocopheryl succinate toxicity.
bioRxiv · Dec 6, 2019Cancer Biology