Influenza A Viral Burst Size from Thousands of Infected Single Cells Using Droplet Quantitative PCR (dqPCR)
G. K. Zath, M. M. Thomas, E. K. Loveday, D. A. Bikos, S. Sanche, R. Ke, c. brooke, C. B. Chang
This study measures viral burst sizes in thousands of infected cells using dqPCR, finding significant variation in H3N2 and H1N1 strains with a small fraction of cells producing most viruses.
bioRxiv · Feb 23, 2024Bioengineering