Author

C. Brooke

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:dimensionality reduction· 1

Frequent Co-Authors

R. Ke· 2 shared A. Farrell· 1 shared C. B. Chang· 1 shared D. A. Bikos· 1 shared D. Ranoa· 1 shared E. K. Loveday· 1 shared F. G. Alnaji· 1 shared G. K. Zath· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersBioengineering

R. Ke

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Influenza A Viral Burst Size from Thousands of Infected Single Cells Using Droplet Quantitative PCR (dqPCR)

G. K. Zath, M. M. Thomas, E. K. Loveday, D. A. Bikos, S. Sanche, R. Ke, c. brooke, C. B. Chang

This study measures viral burst sizes in thousands of infected cells using dqPCR, finding significant variation in H3N2 and H1N1 strains with a small fraction of cells producing most viruses.

bioRxiv · Feb 23, 2024Bioengineering

Saliva-Based Molecular Testing for SARS-CoV-2 that Bypasses RNA Extraction

D. Ranoa, R. Holland, F. G. Alnaji, K. Green, L. Wang, C. Brooke, M. Burke, T. Fan, P. J. Hergenrother

This paper describes a saliva-based SARS-CoV-2 testing method that avoids RNA extraction, achieving a detection limit comparable to nasal swabs and showing good performance with clinical samples.

bioRxiv · Jun 18, 2020 · PreprintMicrobiology

Coinfection of semi-infectious particles can contribute substantially to influenza infection dynamics

A. Farrell, C. Brooke, K. Koelle, R. Ke

The paper models the role of semi-infectious particles and coinfection in influenza dynamics, finding SIPs significantly contribute to viral load and co-infection is frequent during early infection.

bioRxiv · Feb 12, 2019 · PreprintMicrobiology