Endoglin, a novel biomarker and therapeutical target to prevent malignant peripheral nerve sheath tumor growth and metastasis
T. Gonzalez-Munoz, A. Di Giannatale, S. Garcia-Silva…·H. Peinado
This study identifies endoglin (ENG) as a biomarker and therapeutic target for MPNSTs, showing that targeting ENG with antibodies or combining it with MEK inhibitors reduces tumor growth and metastasis.