Separation of function mutations in microcephaly protein CPAP/CENPJ, reveal its role in regulating centriole number and length.
S. Jaiswal, S. Sanghi, P. Singh
This paper identifies two mutations in CPAP affecting centriole length and number through distinct mechanisms, revealing their impact on centriole assembly and STIL interaction.
bioRxiv · Feb 7, 2023 · PreprintCell Biology