SAR1 paralogs differ biochemically in assembly of the COPII coat
D. B. Melville, S. Studer, R. Schekman
The paper identifies paralog-specific amino acid clusters in SAR1 that affect GTP exchange kinetics and SEC23A binding, revealing functional differences between SAR1A and SAR1B in COPII coat assembly and lipoprotein secretion.
bioRxiv · Feb 9, 2020 · PreprintCell Biology