Author

S. T. Joy

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

M. J. Henley· 2 shared A. J. L. Huldin· 1 shared A. K. Mapp· 1 shared A. Mapp· 1 shared I. W. Vock· 1 shared J. A. Yates· 1 shared M. J. Beyersdorf· 1 shared S. D. Merajver· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiochemistry

M. J. Henley

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2 papers

Recent·Most cited

BiochemistrybioRxivSep 3, 2023

Inhibition of CREB binding and function with a dual-targeting ligand

Y. Liu, S. T. Joy, M. J. Henley…·A. K. Mapp

This study develops a dual-targeting ligand, CREBLL-tide, that inhibits the KIX-CREB PPI with high potency and selectivity, showing anti-proliferation activity in breast cancer cells.

DOI 10.1021/acs.biochem.3c00469

humanexperimental assay

BiochemistrybioRxivApr 28, 2021

A Dual-Site Inhibitor of CBP/p300 KIX is a Selective and Effective Modulator of Myb

S. T. Joy, M. J. Henley, S. N. De Salle…·A. Mapp

This paper develops a dual-site inhibitor, MybLL-tide, that selectively targets the CBP/p300 KIX domain, inhibiting Myb-dependent gene expression in AML cells.

DOI 10.1021/jacs.1c04432

humanexperimental assay