Inline Liquid Chromatography-Fast Photochemical Oxidation of Proteins Allows for Targeted Structural Analysis of Conformationally Heterogeneous Mixtures
S. Tadi, S. K. Misra, J. S. Sharp
The paper introduces LC-FPOP to analyze conformationally heterogeneous protein mixtures, showing it provides accurate conformer-specific footprints compared to pure samples.
bioRxiv · Oct 19, 2020Biochemistry