DSS-induced inflammation in the colon drives a pro-inflammatory signature in the brain that is ameliorated by prophylactic treatment with the S100A9 inhibitor paquinimod
S. Talley, R. Valiauga, L. Anderson, A. R. Cannon, M. A. Choudhry, E. M. Campbell
This study shows that colonic inflammation from DSS induces a pro-inflammatory brain signature, which is reduced by S100A9 inhibitor paquinimod.
bioRxiv · Sep 22, 2021 · PreprintImmunology