The In Vivo Source of Type I and Type III IFNs is Pathogen Dependent
M. J. Sandoval, H.-C. Tseng, H. P. Risman, S. Smirnov, Q. Li, J.-D. Lin, A. Rivera, R. K. Durbin, S. V. Kotenko, J. Durbin
This study identifies pathogen-dependent sources of type I and III IFNs during respiratory virus infection, showing that pDCs produce IFN-{lambda} during IAV infection but not NDV.
bioRxiv · Oct 5, 2021 · PreprintImmunology