The fluid membrane determines mechanics of red blood cell extracellular vesicles and is softened in hereditary spherocytosis
D. Vorselen, S. van Dommelen, R. Sorkin, J. Schiller, R. van Wijk, R. Schiffelers, G. Wuite, W. Roos
This study uses atomic force microscopy to analyze the mechanical properties of red blood cell extracellular vesicles from healthy individuals and a hereditary spherocytosis patient, finding that vesicles have a lower bending modulus in the disease state.
bioRxiv · Nov 1, 2017Biophysics