Large-scale allosteric switch in the 7SK RNA regulates transcription in response to growth and stress
S. W. Olson, A.-M. W. Turner, J. W. Arney, I. Saleem, C. A. Weidmann, D. M. Margolis, K. M. Weeks, A. M. Mustoe
The paper introduces DANCE-MaP, a chemical probing strategy to characterize RNA structure and dynamics, revealing 7SK RNA's structural switch regulates transcription in response to growth and stress.
bioRxiv · Sep 16, 2021 · PreprintBiochemistry