Cytokine interaction networks, not individual cytokines, drive anti-TNF response in Crohn's disease
Marton L. Olbei, John P. Thomas, Yufan Liu, Sadek Malas, Dezső Módos, Nick Powell, Tamas Douglas Korcsmaros
The paper identifies cytokine interaction networks, not individual cytokines, as the driver of anti-TNF non-response in Crohn's disease using single-cell RNA sequencing data.
bioRxiv · Aug 11, 2026 · PreprintSystems Biology