Author

Samantha Schultz

University of Massachusetts Amherst

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1

Frequent Co-Authors

Jacob MilesiD· 2 shared Mandy MulleriD· 2 shared Will Dwyer· 2 shared Daniel Macveigh-FierroiD· 1 shared David DeCoeuriD· 1 shared Jianhan CheniD· 1 shared Min CheniD· 1 shared Yahaira BermudeziD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

8 top collaborators · 12 mutual co-author links

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2 shared papersMicrobiology

Jacob MilesORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Single-Molecule Nanopore Profiling of p53-TAD Conformational Dynamics, Interactions, and Inhibition

David DeCoeur, Samantha Schultz, Jianhan Chen, Min Chen

This study uses a nanopore platform to analyze the conformational dynamics and interactions of p53-TAD, showing how a mutation and a drug affect its structure and binding.

bioRxiv · Aug 29, 2026 · PreprintBiophysics

Virally encoded interleukin-6 (vIL-6) coordinates with human IL-6 to modulate cytokine expression during KSHV infection

Yahaira Bermudez, Samantha Schultz, Jacob Miles, Will Dwyer, Mandy Muller

This study shows that viral IL-6 (vIL-6) and human IL-6 work together to influence cytokine expression and immune responses during KSHV infection.

bioRxiv · Oct 2, 2025 · PreprintMicrobiology

IL-6 Evades KSHV-Mediated Hyperadenylation repression via CRM1-Dependent Nuclear Export.

Samantha Schultz, Jacob Miles, Will Dwyer, Daniel Macveigh-Fierro, Mandy Muller

The paper shows that IL-6 mRNA escapes KSHV-induced nuclear retention via CRM1-dependent export, bypassing SOX-mediated decay and maintaining cytoplasmic stability.

bioRxiv · Jun 5, 2025 · PreprintMicrobiology