Microglial engulfing of glutamatergic inputs and diminished excitability of D1 medium spiny neurons of the nucleus accumbens by peripheral inflammatory insult
Shingo Nakajima, Anita Kabahizi, Solal Aubailly, Samar Naili-Douaouda, Akari Tomita, Anthony Bosson, Ciaran Murphy‐Royal, Stephanie E. Fulton
This study shows that peripheral inflammation reduces D1-MSN excitability in the NAc by increasing microglial engulfment of glutamatergic inputs.
bioRxiv · Dec 2, 2024 · PreprintNeuroscience