Multilevel engineering of cyanobacterial energy metabolism advances photosynthetic hydrogen production while revealing its constraints
Marvin Amadeus Itzenhäuser, Samuel Grimm, Lara Ruprecht, Johanna Wiedener, Fabian Brandenburg, Ron Stauder, Pål William Wallace, Jens Olaf Krömer, Andreas Schmid, Stephan Klähn
This study enhances cyanobacterial photosynthetic hydrogen production by addressing multiple metabolic constraints, achieving higher yields but also revealing trade-offs with metabolic stability.
bioRxiv · Jul 22, 2026 · PreprintBioengineering