Author

Samuel Mitchell

University of Minnesota

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Assay:scRNA-seq· 1

Frequent Co-Authors

Elizabeth W. BradleyiD· 3 shared Elizabeth K. Vu· 2 shared Ismael Y. KarkacheiD· 2 shared Nobuaki KikyoiD· 2 shared Nobuko Katoku-KikyoiD· 2 shared Elizabeth K Vu· 1 shared Emily Patterson· 1 shared Ismael Y Karkache· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersCell Biology

Elizabeth W. BradleyORCID

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3 papers

Recent·Most cited

Sex-specific bone marrow populations regulate skeletal phenotype and identify CD74-marked osteoclast precursor subsets

Jinsha Koroth, Ismael Y Karkache, Elizabeth K Vu, Joseph C Manser, Samuel Mitchell, Mitchell J Shimak, Nole Robertson, Emily Patterson, Sydney Kiraguri, Kim M. Mansky, Elizabeth Bradley

The paper identifies sex-specific bone marrow cell populations that regulate bone mass and shows CD74 marks osteoclast precursor subsets.

bioRxiv · Nov 4, 2026 · PreprintCell Biology

The circadian regulator PER1 inhibits osteoclastogenesis by activating inflammatory genes

Nobuko Katoku-Kikyo, Elizabeth K. Vu, Samuel Mitchell, Ismael Y. Karkache, Elizabeth W. Bradley, Nobuaki Kikyo

This study shows that PER1 inhibits osteoclastogenesis by upregulating inflammatory genes, linking circadian rhythms to bone remodeling and suggesting therapeutic targets for inflammatory bone diseases.

Journal of Bone and Mineral Research · Feb 4, 2026Peer-reviewedDevelopmental Biology

Circadian regulators PER1 and PER2 regulate osteoclastogenesis by balancing competing activities of innate immunity genes

Nobuko Katoku-Kikyo, Elizabeth K. Vu, Samuel Mitchell, Ismael Y. Karkache, Elizabeth W. Bradley, Nobuaki Kikyo

This study shows that PER1 and PER2 regulate osteoclastogenesis by balancing innate immunity gene activities, with distinct effects in single and double knockouts.

bioRxiv · Jan 11, 2026 · PreprintCell Biology