Orbitrap Collision Cross Section Measurements Enhance Isomer Annotations in Lipidomics
Ziqin Ni, Konstantin Ayzikov, Alexander Makarov, Samuel Moore, David A. Gaul, Kyle L. Fort, Facundo M. Fernández
This paper introduces a method to infer lipid CCS values from LC-Orbitrap MS data, improving isomer annotation in lipidomics with high precision and accuracy.
bioRxiv · Jul 4, 2026 · PreprintBiochemistry