Author

Sandra Siemann

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:scRNA-seq· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:experimental assay· 1 Research Focus:GWAS / association mapping· 1

Frequent Co-Authors

Alexandra MorganiD· 2 shared Dinesh KumariD· 2 shared Florian RubeltiD· 2 shared Hahn Zhao· 2 shared Hamid Mirebrahim· 2 shared Michie Yasuda· 2 shared Ramy Arnaout (263589)iD· 2 shared Rena Adachi· 2 shared

Activity by Year

2020-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

Alexandra MorganORCID

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Author profile →

3 papers

Recent·Most cited

Accurate Reconstruction of Adaptive Immune Receptor Repertoires from FACS-partitioned B and T Cell Subsets

Hahn Zhao, Alexandra Morgan, Michie Yasuda, Hamid Mirebrahim, Ulrich Schlecht, Sylvie McNamara, Rena Adachi, Sandra Siemann, Florian Rubelt, Dinesh Kumar, Sowmi Utiramerur, Ramy Arnaout (263589), Hosseinali Asgharian

The paper develops computational methods to accurately reconstruct adaptive immune receptor repertoires from partitioned B and T cell subsets, showing improved accuracy compared to pooling sub-repertoires.

bioRxiv · Oct 8, 2026 · PreprintImmunology

HuBIE: The Human Blood Immunome Encyclopedia Of TCRs and BCRs in Bloodstream Infections and Cancer

Vahid Akbari, Alexandra Morgan, Michie Yasuda, Ulrich Schlecht, Sylvie McNamara, Hossein Asgharian, Christopher Tam, Rena Adachi, Elisa Contreras, Zhipei Gracie Du, Sandra Siemann, Hahn Zhao, Jeyashree Ashok Balasubramanian, Diane Balallo, Devanshee Sanghvi, , Ramy Arnaout

HuBIE provides a large-scale immune-repertoire dataset from 1,941 participants, revealing ethnic and age-related differences in TCR and BCR diversity and linking immunological diversity to survival in elderly patients.

Frontiers in Immunology · Jun 18, 2026Peer-reviewedImmunology

HLA-C* 04:01 is a Genetic Risk Allele for Severe Course of COVID-19

Weiner January, Phillip Suwalski, Manuel Holtgrewe, Charlotte Thibeault, Melina Müller, Dimitri Patriki, Claudia Quedenau, Ulrike Krüger, Tania Elisa, Lena Johanna Lippert, Stubbemann Paula, Real Luis Miguel, Sanchez Juan Macias, A. Pineda Juan, Marta Fernández‐Fuertes, , Bettina Heidecker

The paper identifies HLA-C* 04:01 as a genetic risk allele associated with increased intubation risk in severe COVID-19 cases, validated across multiple cohorts.

medRxiv · Dec 21, 2020 · PreprintGenetic & Genomic Medicine