Author

Sara Cherry

University of Pennsylvania

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:Drosophila· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Swechha Mainali PokhareliD· 2 shared Adam J. GilbertseniD· 1 shared Ana M. Misic· 1 shared Anne Rivas· 1 shared Arno Wuenschmann· 1 shared Beth Gold· 1 shared Celia Torres-AranciviaiD· 1 shared Cera A. McDonaldiD· 1 shared

Activity by Year

2017-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersImmunology

Swechha Mainali PokharelORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A mammalian fibroblast zoo reveals barriers to cross-species virus replication and differential regulation of antiviral immunity

Clayton K. Mickelson, Mark Salnikov, Frances K. Shepherd, Lauren M. Pross, Georgia McClain, Swechha Mainali Pokharel, H. Heinrich Hoffmann, Timo Schoon, Girish Pulinkala, Nakarin Pamornchainavakul, Kayla Hoffman, Cera A. McDonald, Esther Vogt, Tristan T. Neal, Adam J. Gilbertsen, , Ryan A. Langlois

The paper uses fibroblasts from 86 mammalian species to study virus-host susceptibility and innate immune responses across diverse mammals.

bioRxiv · Nov 6, 2026 · PreprintImmunology

A dynamic molecular glue targets a plastic MDA5 filament interface to stimulate innate immunity

闫丽娟, 闫丽娟, Ziqing Ye, Swechha Mainali Pokharel, Tiffany Y. T. Hsu, Celia Torres-Arancivia, Koji Haratani, Elena V. Ivanova, Cloud Peter Paweletz, Sara Cherry, David Allen Barbie, Sun Hur

This paper identifies MA2, a small-molecule agonist of MDA5 that enhances antiviral and antitumor immunity by dynamically stabilizing MDA5 filaments.

bioRxiv · Oct 20, 2026 · PreprintImmunology

Aging-associated dysbiosis increases susceptibility to enteric viral infection in Drosophila

Christine Sansone, Jonathan Cohen, Beth Gold, Wenhan Zhu, Ana M. Misic, Daniel P. Beiting, Sebastian E. Winter, Sara Cherry

This study shows that aging in Drosophila leads to microbiota dysbiosis, increasing susceptibility to enteric viral infections, and that restoring the microbiota can recover immune function.

bioRxiv · Jun 27, 2017 · PreprintImmunology