Author

Shaorong Chen

Westlake University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 2

Signature Assays, Organisms & Methods

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Assay:proteomics· 2 Research Focus:deconvolution· 1 Approach:deep learning· 1 Organism:human· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1 Approach:transformer / foundation model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Jun XiaiD· 2 shared Cheng ChangiD· 1 shared Fan Xu· 1 shared Fuchu He· 1 shared Guibin Wang· 1 shared Hongxin XiangiD· 1 shared Jingbo ZhouiD· 1 shared Jun ZhuiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersBioinformatics

Jun XiaORCID

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2 papers

Recent·Most cited

π-SPECFormer: A Mass Spectrometry-based Foundation Model for Decoding the Dark Proteome

Tianze Ling, Tao Liu, Fan Xu, Yiming Zhang, Jun Xia, Xiansong Huang, Shaorong Chen, Linhai Xie, Rong Xu, Tingpeng Yang, Kaixuan Li, Guibin Wang, Zhendong Liang, Jun Zhu, Stan Z. Li, , Cheng Chang

This paper introduces π-SPECFormer, a foundation model for mass spectrometry-based proteomics that decodes the dark proteome by pre-training on unannotated spectra and outperforms baselines in peptide sequencing and modification detection.

bioRxiv · Nov 9, 2026 · PreprintBioinformatics

Bridging the Gap between Database Search and De Novo Peptide Sequencing with SearchNovo

Jun Xia, Sizhe Liu, Jingbo Zhou, Shaorong Chen, Hongxin Xiang, Zicheng Liu, Yue Liu, Stan Ziqing Li

SearchNovo improves peptide sequencing by combining database search and de novo methods, outperforming existing models on multiple datasets.

bioRxiv · Oct 19, 2024 · PreprintBioinformatics