Author

Simon Weissmann

Leibniz Institute of Virology (LIV)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Assay:DNA methylation· 2 Research Focus:gene regulatory network inference· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Adam T. GrundhoffiD· 4 shared Thomas GüntheriD· 4 shared Marion Ziegler· 2 shared Abel Viejo‐BorbollaiD· 1 shared Alexey V. TerskikhiD· 1 shared Alexis RobitailleiD· 1 shared Benedikt B. KauferiD· 1 shared Birgit RitteriD· 1 shared

Activity by Year

2025-2025 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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4 shared papersMicrobiology

Adam T. GrundhoffORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Oncogenic virus hijacks SOX18 pioneer function to enhance viral persistence

Krista Tuohinto, Matthew S. Graus, Peyton Staab, Ville Tiusanen, Fei Liangru, Susav Pradhan, Yew Yan Wong, Simon Weissmann, Jieqiong Lou, Elizabeth Hinde, Justin Wong, Quintin Lee, Alexey V. Terskikh, Martin Alvarez-Kuglen, Tara Karnezis, , Päivi M. Ojala

This study shows KSHV uses SOX18 to maintain viral episomes in LECs by enhancing chromatin accessibility.

bioRxiv · Jun 28, 2025 · PreprintMolecular Biology

Spatiotemporal analysis of de novo KSHV infection using Crispr/Cas9-based 3D live cell imaging at single episome resolution

Thomas Günther, Simon Weissmann, Martin V. Hamann, Henry Scheibel, Jens B. Bosse, Marion Ziegler, Adam T. Grundhoff

This study develops a CRISPR/Cas9-based 3D live cell imaging system to track KSHV episomes in real-time, revealing their spatiotemporal dynamics during infection.

bioRxiv · Feb 11, 2025 · PreprintMicrobiology

Polycomb group proteins protect latent Kaposi sarcoma-associated herpesvirus from episome clearance and HUSH-dependent chromatin silencing

Simon Weissmann, Alexis Robitaille, Thomas Günther, Marion Ziegler, Adam T. Grundhoff

This study shows that Polycomb group proteins maintain KSHV latency by repressing viral gene expression and protecting episomes from HUSH-dependent silencing.

bioRxiv · Feb 10, 2025 · PreprintMicrobiology

Repression of varicella zoster virus gene expression during quiescent infection in the absence of detectable histone deposition

Jiayi Wang, Nadine Brückner, Simon Weissmann, Thomas Günther, Shuyong Zhu, Carolin Vogt, Guorong Sun, Rongrong Guo, Renzo Bruno, Birgit Ritter, Lars Steinbrück, Benedikt B. Kaufer, Daniel P. Depledge, Adam T. Grundhoff, Abel Viejo‐Borbolla

This study investigates VZV gene repression in neuronal cells, finding that histone deposition is absent at quiescent viral genomes.

PLoS Pathogens · Feb 10, 2025Peer-reviewedMicrobiology