BCL2L13 attenuation links impaired mitophagy to epithelial plasticity and anoikis tolerance in lung adenocarcinoma
Javad Alizadeh, Simone CDS Rosa, Abhay Srivastava, Mahmoud Aghaei, Zeinab Babaei, Aleksandra Głogowska, Amir Barzegar Behrooz, Amir Ravandi, Sabine Hombach‐Klonisch, Sanjiv Dhingra, Michael R. A. Mowat, Rui Vitorino, Joseph W. Gordon, Biniam Kidane, Naseer Ahmed, Saeid Ghavami
This study shows that BCL2L13 downregulation in NSCLC promotes metastasis by impairing mitophagy and enhancing epithelial plasticity and anoikis tolerance.
bioRxiv · Aug 31, 2026 · PreprintCancer Biology