Simone Jung

PERK retains a predominantly monomeric state under ER stress conditions

This study uses fluorescence microscopy to show PERK remains mostly monomeric under ER stress, challenging the idea that oligomerization is required for its activation.

Svep1 stabilizes developmental vascular anastomosis in reduced flow conditions.

This study identifies Svep1 as a factor that stabilizes vascular anastomosis in zebrafish embryos under reduced flow conditions.

Vasohibin-1 mediated tubulin detyrosination selectively regulates secondary sprouting and lymphangiogenesis in the zebrafish trunk

This study shows that Vasohibin-1 mediates tubulin detyrosination in zebrafish endothelial cells, selectively regulating secondary sprouting and lymphangiogenesis in the trunk.

A missense mutation in TUBD1 is associated with high juvenile mortality in Braunvieh and Fleckvieh cattle

This study identifies a missense mutation in TUBD1 linked to high juvenile mortality in Braunvieh and Fleckvieh cattle, associated with chronic airway disease due to defective cilia.

A frameshift mutation in GON4L is associated with proportionate dwarfism in Fleckvieh cattle

The paper identifies a frameshift mutation in GON4L causing dwarfism in Fleckvieh cattle by linking it to growth restriction and craniofacial abnormalities through genomic analysis.