Dissecting embryonic and extra-embryonic lineage crosstalk with stem cell co-culture
Yulei Wei, Enbo Zhang, Leqian Yu, Baiquan Ci, Masahiro Sakurai, Lei Ming Guo, Xin Zhang, Sirui Lin, Shino Takii, Lizhong Liu, Jian Liu, Daniel A. Schmitz, Ting Su, Junmei Zhang, Qiaoyan Shen, , Jun Wu
This study establishes co-cultures of embryonic and extraembryonic stem cells to study lineage crosstalk during early mammalian development, revealing growth inhibition of pluripotent cells by extraembryonic endoderm cells.
Cell · Dec 1, 2023Peer-reviewedDevelopmental Biology