Author

Sofia Cavada-Silva

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Immunology· 1

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Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:spatial transcriptomics· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

Amaury LerusteiD· 1 shared Christine SedlikiD· 1 shared Eliane PiaggioiD· 1 shared Federico MarzialiiD· 1 shared Franck BourdeautiD· 1 shared Hélène D. MoreauiD· 1 shared Jérémie D. GoldsteiniD· 1 shared Jérémy MespleiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Amaury LerusteORCID

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1 paper

Recent·Most cited

Myeloid reprogramming by poly(I:C) recruits progenitor-exhausted CD8+ T cells and sensitizes rhabdoid tumors to PD-1 blockade

Valeria Sandoval Manríquez, Sofia Cavada-Silva, Kévin Beccaria, Leticia Laura Niborski, Amaury Leruste, Wilfrid Richer, Mathias Vandenbogaert, Zhi‐Yan Han, Christine Sedlik, Jordan Denizeau, Jérémy Mesple, Zoé Fusilier, Laëtitia Lesage, Jérémie D. Goldstein, Yohan Gerber-Ferder, , Eliane Piaggio

This study shows that poly(I:C) reprograms myeloid cells in rhabdoid tumors, enhancing CD8+ T cell infiltration and improving response to PD-1 blockade.

bioRxiv · Dec 29, 2025 · PreprintImmunology