Lymph-node transcriptomics define prognostic immune states in mucosal melanoma and reveal IBA1 as a practical biomarker for improved prognosis
Angus Lane, Laura Blackwood, Kevin Donnelly, Yuting Lu, Alison M. Meynert, Jorge del Pozo, Gerry A. Polton, Laura Elizabeth Selmic, Jean‐Benoit Tanis, David R. Killick, Joanna Siriol Morris, Inge Breathnach, Stefano Zago, Sara Gould, Scott Maxwell, , Kelly Bowlt Blacklock
This study identifies two prognostic lymph node subgroups in canine oral mucosal melanoma using transcriptomics, with IBA1 expression linked to improved survival.
bioRxiv · Sep 20, 2025 · PreprintCancer Biology