Stephen E. Chang

Chronic semaglutide treatment attenuates cue-induced reinstatement of cocaine-seeking and cocaine-induced stereotypy in male and female rats

This study shows that chronic semaglutide treatment reduces cue- and cocaine-induced reinstatement of cocaine-seeking in male and female rats.

Differential acquisition of cocaine and heroin self-administration in a rat model of internalizing versus externalizing temperament

This study compares how cocaine and heroin self-administration is acquired in rats with internalizing vs. externalizing temperament, finding drug-specific and sex-dependent differences.

Chronic semaglutide treatment enhances the incentive motivational value of a small food reward and associated cue in male and female rats

This study shows chronic semaglutide increases motivation for food rewards and cues but reduces overall food consumption in rats.

The effect of corticosterone on the acquisition of Pavlovian conditioned approach behavior is dependent on sex and vendor

This study examines how corticosterone affects sign- and goal-tracking behaviors in male and female rats from different vendors, finding sex- and vendor-dependent effects on acquisition but not expression.

Inhibition of a cortico-thalamic circuit attenuates cue-induced reinstatement of drug-seeking behavior in relapse prone male rats

The paper shows that inhibiting the PrL-PVT pathway reduces cue-induced relapse in ST rats but not GT rats, highlighting individual differences in relapse vulnerability.