Author

Stephen Fleming

Broad Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Biophysics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:phylogenetics / evolution· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Anne L PiantadosiiD· 1 shared Bettina BankampiD· 1 shared Bo Lu· 1 shared Brandon Sabina· 1 shared Bridget ChakiD· 1 shared Bronwyn L. MacInnisiD· 1 shared Christian B. Matranga· 1 shared Daniel J. ParkiD· 1 shared

Activity by Year

2015-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperGenomics

Anne L PiantadosiORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Modeling interpretable correspondence between cell state and perturbation response with CellCap

Yang Xu, Stephen Fleming, Matthew Tegtmeyer, Steven A. McCarroll, Mehrtash Babadi

CellCap models the relationship between cell state and perturbation response in single-cell experiments, revealing novel insights into cellular behavior.

bioRxiv · Mar 14, 2024 · PreprintBioinformatics

Co-circulating mumps lineages at multiple geographic scales

Shirlee Wohl, Hayden C. Metsky, Stephen F. Schaffner, Anne L Piantadosi, Meagan Burns, Joseph A. Lewnard, Bridget Chak, Lydia Andreyevna Krasilnikova, Katherine J. Siddle, Christian B. Matranga, Bettina Bankamp, Scott Hennigan, Brandon Sabina, Elizabeth H. Byrne, Rebecca J. McNall, , Pardis Christine Sabeti

The paper analyzes mumps virus circulation in the US using genomic data to show multiple co-circulating lineages and transmission patterns, but finds no evidence of vaccine escape variants.

PLoS Biology · Feb 11, 2020Peer-reviewedGenomics

Thermal motion of DNA in an MspA pore

Bo Lu, Stephen Fleming, Tamas Szalay, Jene A Golovchenko

The paper measures thermal motion of ssDNA in an MspA pore and shows that increasing electrophoretic force reduces thermal averaging.

bioRxiv · Jun 30, 2015Biophysics