Author

Stephen J. Capuzzi

Primary ORCID profile (0000-0003-0001-8211 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Stephen J. CapuzziiD1 paper · University of North Carolina at Chapel Hill

Biology Disciplines

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Pharmacology & Toxicology· 1

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Alessandra Mascarello· 1 shared Alison D. Axtman· 1 shared Carrow I. Wells· 1 shared Cristiano R. W. Guimarães· 1 shared David H. Drewry· 1 shared Hátylas Azevedo· 1 shared Jonathan M. Elkins· 1 shared Opher Gileadi· 1 shared

Activity by Year

2017-2017 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperPharmacology & Toxicology

Alessandra Mascarello

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1 paper

Recent·Most cited

Development of Narrow Spectrum ATP-competitive Kinase Inhibitors as Probes for BIKE and AAK1

Rafael M. Couñago, Alison D. Axtman, Stephen J. Capuzzi, Hátylas Azevedo, David H. Drewry, Jonathan M. Elkins, Opher Gileadi, Cristiano R. W. Guimarães, Alessandra Mascarello, Ricardo A. M. Serafim, Carrow I. Wells, Timothy M. Willson, William J. Zuercher

The paper describes two compounds with minimal structural differences that show significant differential kinase activity, using x-ray crystallography and computational analysis to explain the selectivity.

bioRxiv · Mar 2, 2017 · PreprintPharmacology & Toxicology