Methionine modulates the metabolic-epigenetic axis as immunotherapeutic in tuberculosis
Nidhi Raj Yadav, Ashish Kumar Gupta, Soumya Sahoo, Suchitra Jena, Nainy Goel, Mothe Sravya, Tundup Namgail, Nupur Sharma, Someshwar Nath Jha, Bhishma Narayan Panda, Nimesh Gupta, Jaswinder Singh Maras, Amit Kumar Pandey, Shyam Kumar Masakapalli, Debasis Dash, Ranjan Kumar Nanda
This study shows methionine supplementation enhances pro-inflammatory responses and mycobacterial clearance in tuberculosis by modulating host metabolism and epigenetic pathways.
bioRxiv · Oct 7, 2025 · PreprintImmunology