Therapeutic Salmonella induces long-term protective trained immunity in NK cells against cancer metastasis
Rong Li, Jingchu Hu, Wei Jin, Renhao Li, Yangfan Wu, Nan Zhou, Zhongjun Zhou, Hosen Md Shakhawat, Xiaolei Wang, Shuo Han, Huarui Gong, Xuansheng Lin, Wenjun Li, Yige He, Sukbum Kim, , Jian‐Dong Huang
This study shows that a single dose of Salmonella YB1 vaccine induces long-term protective trained immunity in NK cells, enhancing their ability to combat cancer metastasis.
bioRxiv · Aug 29, 2025 · PreprintImmunology