Defining biologically directed therapy target signatures in urothelial carcinoma: A transcriptomic framework for precision therapy
Edwin Lin, Feng Bing-Jian, Kaniz Fatema, Zeynep İrem Özay, Georges Gebrael, Varun Nandakumar, Ethan G. Murdock, Haoran Li, George Daniel Grass, Eric A. Singer, Laura Graham, Qiang Li, Bodour Salhia, Saum Ghodoussipour, Jennifer M. King, , Sumati Gupta
This paper identifies biologically distinct transcriptomic and proteomic patterns of ADC and immunotherapy targets in urothelial carcinoma, linking them to histologic and molecular subtypes for precision therapy.
bioRxiv · Jun 25, 2026 · PreprintCancer Biology