Author

Sunandini Ramnarayanan

University College Dublin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:gene regulatory network inference· 2 Approach:genetic perturbation / CRISPR· 2 Approach:statistical model· 2 Research Focus:variant calling· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Rory JohnsoniD· 4 shared Ai Ming Tham· 2 shared Hugo Guillen-RamireziD· 2 shared Michela CoaniD· 2 shared Tina Uroda· 2 shared Adrian F. OchsenbeiniD· 1 shared Adrienne VancuraiD· 1 shared Alberto J. ArribasiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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4 shared papersCancer Biology

Rory JohnsonORCID

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Author profile →

4 papers

Recent·Most cited

Pan-cancer discovery of driver mutations in long noncoding RNAs reveals widespread functional rewiring of RNA regulatory elements

Sunandini Ramnarayanan, Roofiya Koya, Marta Soszynska-Jozwiak, Marta Szabat, Jack Roban, Sarang Bhutada, Bhavya Dhaka, Tilman Schaefer, Ai Ming Tham, Hugo Guillen-Ramirez, Francesca Alessandroni, Michela Coan, Artem Baranovskii, Lambert Moyon, Annalisa Marsico, , Rory Johnson

The paper identifies 121 lncRNA driver mutations across 19 cancer types using 12,631 genomes, showing mutations disrupt RNA-binding protein interactions to promote oncogenesis.

bioRxiv · Jun 12, 2026 · PreprintCancer Biology

Robust CRISPR Screens Identify TPL1 as a Novel Long Noncoding RNA Driving Triple-Negative Breast Cancer Hallmarks

Ramesh Elango, Sunandini Ramnarayanan, Radhakrishnan Vishnubalaji, Lütfiye Yıldız Özer, Michela Coan, Yifan Yu, Sunkyu Choi, Tina Uroda, Carlos Pulido-Quetglas, Frank Schmidt, Khalid Ouararhni, Ayman Al Haj Zen, Rory Johnson, Nehad M. Alajez

The paper identifies TPL1 as a novel long noncoding RNA that drives triple-negative breast cancer hallmarks through multiple molecular mechanisms.

bioRxiv · Aug 6, 2025 · PreprintCancer Biology

Enhancer lncRNA LOC730338 modulates BCR signaling and immune evasion in lymphoma by regulating RNA homeostasis.

Luciano Cascione, Francesca Guidetti, Sunandini Ramnarayanan, Andrea Rinaldi, Filippo Spriano, Alex Zadro, Chiara Tarantelli, Serena Zambarbieri, Nicolas Munz, Simone Avesani, Alberto J. Arribas, Rosalba Giugno, Rory Johnson, Francesco Bertoni, Sara Napoli

This paper identifies ADARreg, an elncRNA that modulates BCR signaling and immune evasion in lymphoma by altering RNA stability, localization, and editing, providing a potential therapeutic target.

bioRxiv · Dec 10, 2024 · PreprintCancer Biology

Tumour mutations in long noncoding RNAs enhance cell fitness

Roberta Esposito, Andrés Lanzós, Tina Uroda, Sunandini Ramnarayanan, Isabel Büchi, Taisia Polidori, Hugo Guillen-Ramirez, Ante Mihaljevic, Bernard Mefi Merlin, Lia Mela, Eugenio Zoni, Lusine Hovhannisyan, Finn McCluggage, Matúš Medo, Giulia Basile, , Rory Johnson

The paper identifies mutated long noncoding RNAs (lncRNAs) as contributors to tumour cell fitness through experimental validation of their oncogenic effects.

Nature Communications · Jun 8, 2023Peer-reviewedGenomics