Author

Sunir Malla

GlaxoSmithKline (United Kingdom)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Assay:long-read sequencing· 2 Approach:benchmark study· 1 Research Focus:benchmarking· 1 Assay:CRISPR screen· 1 Research Focus:database / resource· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Matthew LooseiD· 2 shared Aaron R. QuinlaniD· 1 shared Adam Krejčí· 1 shared Adam M. PhillippyiD· 1 shared Adrián CortésiD· 1 shared Alexander DiltheyiD· 1 shared Alison Acevedo· 1 shared Andrew David BeggsiD· 1 shared

Activity by Year

2016-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersGenomics

Matthew LooseORCID

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Author profile →

3 papers

Recent·Most cited

Mapping the functional impact of non-coding regulatory elements in primary T cells through single-cell CRISPR screens

Celia Alda-Catalinas, Ximena Ibarra-Soria, Christina Flouri, Jorge Esparza Gordillo, Diana L. Cousminer, Anna Hutchinson, Adam Krejčí, Adrián Cortés, Alison Acevedo, Sunir Malla, Carl Fishwick, Gerard Drewes, Radu Rapiteanu

The paper develops a CRISPRi-based single-cell screening approach to map non-coding regulatory elements to genes in primary human CD4+ T cells and demonstrates its utility for GWAS effector gene identification.

bioRxiv · May 14, 2023 · PreprintGenomics

Nanopore sequencing and assembly of a human genome with ultra-long reads

Miten Jain, Sergey Koren, Karen H. Miga, Josh Quick, Arthur C Rand, Thomas A. Sasani, John R. Tyson, Andrew David Beggs, Alexander Dilthey, Ian T. Fiddes, Sunir Malla, Hannah Marriott, Tom Nieto, Justin O’Grady, Hugh E. Olsen, , Matthew Loose

Nanopore-only sequencing of GM12878 across 39 MinION flowcells (91.2 Gb) yielded an assembly with NG50 ∼3 Mb; adding 5× ultra-long reads raised NG50 to 6.4 Mbp.

Nature Biotechnology · Jan 29, 2018Peer-reviewedGenomics✦ In-depth digest

Real time selective sequencing using nanopore technology.

Matthew Loose, Sunir Malla, Michael Stout

This paper demonstrates real-time selective DNA sequencing using the MinION device by matching current traces to references and selecting specific DNA regions.

Nature Methods · Jul 25, 2016Peer-reviewedGenomics