Label-free identification and classification of leukocyte subpopulations in peripheral blood smears by optical photothermal infrared spectroscopy
Shravan Raghunathan, Susann Piehler, Cornelia Reuter, Michael Kiehntopf, Jürgen Popp, Christoph Krafft
This paper uses optical photothermal infrared spectroscopy to classify leukocyte subpopulations in blood smears without staining, achieving accurate separation of granulocytes, lymphocytes, and monocytes.
bioRxiv · Oct 20, 2026 · PreprintBiophysics