Mitochondrial amino acid export preserves mitochondrial volume at the egg-to-embryo transition
Melissa C. Pamula, Lauren Clamon, Samuel Block, Suzanne Savage, Christoph G. Gäbelein, Ashid Amarsanaa, Margaret E. Bisher, David V. Mankus, Abigail K. R. Lytton‐Jean, Nora Kory, Ruth Lehmann
The paper identifies Sfxn1-3's role in regulating mitochondrial volume during the egg-to-embryo transition by controlling amino acid export and osmotic balance.
bioRxiv · Oct 9, 2026 · PreprintDevelopmental Biology